When we as humans would be angry at the foolishness of man’s sin, God, in His mercy, gives us a promise. “And I will put enmity between thee and the woman, and between thy seed and her seed; it shall bruise thy head, and thou shalt bruise his heel” (Genesis 3:15). In speaking to the serpent, God made a promise of ultimate victory for man. Woman caused the fall, and a woman was to be the source of redemption.
The remainder of the Bible is a development of this promise. In the Old Testament- He is coming. The Gospels say-He has arrived. The epistles tell us-He is coming again.
The promise of Genesis 3:15 not only gave the hope of a Redeemer who would contend with Satan and overcome him, but also implied that there would be perpetual enmity between the opposing seeds in the world. The seed of the serpent and the seed, or spiritual children, of the Deliverer would be in a continual conflict of opposing each other.
The one would bruise the heel of his opponent, but the other would ultimately bruise his head, or destroy his usurped authority in the world and overthrow his kingdom. Thus a perpetual warfare is declared between the kingdom of God and the kingdom of the devil among men. Jesus once said to the wicked, “Ye are of your father the devil,” or in other words, “the seed of the serpent.”